Betty Edem Nugba
- Country of Origin: Ghana
- Home University: University of Ghana
- Host University & Country: University of Miami - USA
- PhD Title: The role of cohesin and chromosome architecture in promoting breast cancer progression
- Year of Completion: 2028
PhD Overview
Metastatic dissemination is a hallmark of breast cancer malignancy, making the disease. A critical step in enabling dissemination to distal tissues is epithelial-mesenchymal transition, EMT), which allows cells to intravasate, travel in circulation, and finally colonize secondary sites. EMT is an epigenetically regulated phenotype for which several transcription factors have been identified. However, the role of 3D genome organization is less clear. We hypothesize that the cohesin complex plays a necessary role during the chromosomal architectural changes that enable the establishment of the mesenchymal transcriptional program as part of the EMT process.
Sustainability Goals
- Good Health and Well-being
About Me
My academic and research journey started at 15 at the University of Ghana when I begun my Undergraduate studies. I was then awarded the TICAD7 scholarship as the first Ghanaian woman at the time to pursue my Master’s in Egypt. Now I am pursuing my PhD, advancing my research in breast cancer.